Resident Evil 4
aka RE4, Biohazard 4 (JPN)
Genre: Third-Person Action Adventure
Number of Players: 1
The fourth installment of Capcom's pivotal "Survival Horror" series continues with this fully-3D installment. The title takes place in 2004 some six years after the events that transpired in Resident Evil 2. The government has destroyed the Umbrella Corporation, which has been behind just about every plot and disgusting bio-chemical mutation in the survival horror series. Now-US agent Leon Kennedy (of Resident Evil 2 fame) has been dispatched to Europe to save the President's daughter from "crazed organizations."
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Yup, I know it's a very old game on the PS2 but I thought I'd give a heads up for PC gamers. It's out na

But sadly no mouse support according to the various forums...