if ur mobo is 1600 capable..no need to OC the bios will automatically handle the ram sticks
if 1333 ra kutob ang mobo , mu step down ur ram into the max ram speed the mobo can handle but with a tighter CAS settings
or u OC ur Procie with Assync or Sync settng RAM : FSB , that will make ur Mobo ran the RAM into a OC result relaxed 1600MHz speed < this is the gud thing on RAM with higher than mobo limitation speed




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ike one comment that 8gb - 16gb wont give any difference yet for now, , ,so base ana, i'd go for 8gb lang temporarily, then kung naa nay support, or makatigom, id updgrade my other hardware components 
