Colon cancer is most commonly treated through the use of surgery. The doctor will remove the tumor, as well as some of the healthy tissue and lymph nodes in the area. If the cancer has not metastasized (spread to other areas), surgery may be the only treatment required. If the colon cancer is advanced and spread, however, a cure is unlikely. For those with a tumor that has deeply penetrated the colon wall or has spread to nearby lymph nodes, chemotherapy can be instrumental in preventing a recurrence of the cancer. Doctors may also determine that it is beneficial to introduce chemotherapeutic agents directly into the liver, as it is the place most likely to be affected by metastasis.